Overexpression of RORγt Enhances Pulmonary Inflammation after Infection with Mycobacterium Avium
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منابع مشابه
Overexpression of RORγt Enhances Pulmonary Inflammation after Infection with Mycobacterium Avium
Mycobacterium avium complex (MAC) is the most common cause of nontuberculous mycobacterial disease in humans. The role of Th17 immunity in the pathogenesis of intracellular bacteria, such as MAC, is not currently understood. Transcription factor RAR-related orphan receptor gamma t (RORγt) is known as the master regulator for Th17 cell development. Here, we investigated the role of RORγt in host...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2016
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0147064